Defining the future of treatment for people with immune-mediated diseases

About

Building the leading immune reset company.

We founded Ouro Medicines to build the leading immune reset company. We tackle chronic immune-mediated diseases head-on by combining scientific expertise, a track record of advancing cell-depleting therapies through the clinic, and a robust pipeline.

Science

An ideal modality for cell depletion.

With high potency and specificity, T cells engagers (TCEs) represent an off-the-shelf therapeutic modality for resetting the immune system by depleting the proinflammatory cells underlying many immune-mediated diseases. Initial data with TCEs demonstrate the potential to achieve  immunological “reset” and induce durable remissions without the need for ongoing immunosuppression.

We plan to evaluate our lead therapeutic candidate, OM336, in a range of IMDs. Behind our lead program, we are advancing a set of discovery programs targeting additional dimensions of B cell biology. These programs probe unique subsets of B cells that may prove key to achieving longer remissions for patients with certain diseases. 

b cell photo

Validated targets for B cell lineage depletion

engager photo

Premier T cell engager platform

biology photo

Clinical positioning informed by disease biology

Pipeline

desktop pipeline

mobile pipeline


*Ongoing studies for 336 in the treatment of Multiple Myeloma are sponsored by KeyMed Biosciences.

Team

Ouro’s team is driven to develop immune reset therapeutics for people living with chronic immune-mediated diseases.

Leadership

neely mozaffarian photo

Neely Mozaffarian, MD, PhD

Chief Medical Officer

kevin baker photo

Kevin P. Baker, PhD

Chief Development Officer

Christina Carlson photo

Christina Carlson, JD 

Chief Administrative Officer

Board of Directors

Bo Chen, PhD

KeyMed

Jaideep Dudani, PhD

CEO

Tim Funnell, DPhil

Monograph Capital

Shinichiro Fuse, PhD

TPG

Brian Matesic, MD

Norwest

Matt McAviney, MD

NEA

Clinical Advisors

Matthew Baker, MD, MS

John C Davis Jr, MD, MPH, MS

Stanford Peng, MD, PhD

Investors

Monograph Capital logo
TPG Global, LLC logo
New Enterprise Associates (NEA) logo
Norwest logo
Glaxo Group Limited logo
UPMC logo
BoYu logo
Long River logo